irrespective of的意思是什么

造句：

1.As the founder of the company, he is self-willed, never considering whether his actions are good for the company.

作为公司创始人，他一意孤行，从不考虑其行为是不是对企业有利。

2.Experts point out that a rash of rural urbanization without regard to environmental protection, social security and industrial development will inevitably feed tigers.

专家指出，不考虑环保、社保和产业发展等情况的一哄而上式农村城市化建设必将养虎为患。